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Symbol
Name
ID
Rac1
Rac family small GTPase 1
MGI:97845
Phenotype annotations related to renal/urinary system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Hypospadias
Renal cell carcinoma
Disease(s) Associated with RAC1
autosomal dominant intellectual developmental disorder 48
colorectal cancer

Mouse Phenotypes
renal/urinary system phenotype
increased urine protein level
podocyte foot process effacement
small kidney
Availability Mouse Genotype
Rac1em1(IMPC)Mbp/Rac1+
Hprt1tm1(tetO-EGFP/Rac1*)Shaw/Y *
Hprt1tm1(tetO-EGFP/Rac1*)Shaw/Y
Tg(NPHS2-rtTA2*M2)1Jbk/0
Hprt1tm1(tetO-EGFP/Rac1*)Shaw/Y
Tg(Nphs1-rtTA*3G)8Jhm/0
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory